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Episode 37. Why We Get Fat And What We Can Do About It with Professor Joseph Proietto

The western world faces a very significant obesity epidemic. In Australia, two-thirds of our population or 12.5 million are either overweight or obese and as a consequence may experience many medical sequelae including development of the metabolic syndrome, type 2 diabetes, cardiovascular disease, cerebrovascular disease, osteoarthritis and depression, contributing significantly to our health burden. In the first part of this series, we were joined by Joseph Proietto, Professor Emeritus at the University of Melbourne, the Department of Medicine at Austin Health and an endocrinologist specialising in diabetes and obesity to discuss why we become obese. Professor Proietto joins us again to guide us through a strategy of how to treat and manage obesity and direct our patients toward a healthy body mass index (BMI).

The western world faces a very significant obesity epidemic. In Australia, two-thirds of our population or 12.5 million are either overweight or obese and as a consequence may experience many medical sequelae including development of the metabolic syndrome, type 2 diabetes, cardiovascular disease, cerebrovascular disease, osteoarthritis and depression, contributing significantly to our health burden. In the first part of this series, we were joined by Joseph Proietto, Professor Emeritus at the University of Melbourne, the Department of Medicine at Austin Health and an endocrinologist specialising in diabetes and obesity to discuss why we become obese. Professor Proietto joins us again to guide us through a strategy of how to treat and manage obesity and direct our patients toward a healthy body mass index (BMI).

In this episode Professor Proietto discusses:

· The concept of energy balance

· The influence of exercise

· Dietary approaches including - Very low energy diets that induce a ketogenic state

· Medication used to suppress appetite and assist patients to establish an optimal BMI

Professor Proietto was extremely informative in this conversation navigating steadily and logically through a management strategy that may be applied to our patients experiencing obesity in primary practice. Thank you for joining me in this conversation.

Useful references include:

www.endocrine.net.au

www.darebinweightlosssurgery.com.au

- vermontsouthmedicalcentre.com.au

- Body Weight Regulation – Essential Knowledge to Lose Weight and Keep It Off by Joseph Proietto. ISBN 9781514497005. Published 12 August 2016, Publisher Xlibris.

www.aihw.gov.au

- pubmed.ncbi.nlm.nih.gov

www.sciencedirect.com

To be a guest on the show or provide some feedback, I’d love to hear from you: manager@gihealth.com.au

Dr Luke Crantock MBBS, FRACP, is a gastroenterologist in practice for over 25 years. He is the founder of The Centre for GI Health, based in Melbourne Australia and is passionate about educating General Practitioners and patients on disease prevention and how to manage and improve their digestive health.

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Block 2 Centre for GI Health Block 2 Centre for GI Health

Episode 36. Why We Get Fat with Professor Joseph Proietto

Up to two thirds of Australians are either overweight or obese as defined by body mass index (overweight: BMI 25-29.9, obese: BMI >30) with subsequent significant medical consequences including cardiovascular disease, type 2 diabetes, cerebrovascular disease (metabolic syndrome), osteoarthritis and depression. Becoming overweight and obese involves complex interactions between neurohormonal systems of the gut, neurobiology of the brain (particularly the hypothalamus) and leptin production from adipose sites coupled with an environment where there is an abundance of high glycaemic energy dense foods. Science demonstrates that the overarching controls of obesity are genetic (70%) rather than environmental (30%). Adoption studies relating to monozygotic twins demonstrate this. In view of the metabolic consequences of obesity, understanding why we get fat is extremely important to medical practitioners.

Up to two thirds of Australians are either overweight or obese as defined by body mass index (overweight: BMI 25-29.9, obese: BMI >30) with subsequent significant medical consequences including cardiovascular disease, type 2 diabetes, cerebrovascular disease (metabolic syndrome), osteoarthritis and depression. Becoming overweight and obese involves complex interactions between neurohormonal systems of the gut, neurobiology of the brain (particularly the hypothalamus) and leptin production from adipose sites coupled with an environment where there is an abundance of high glycaemic energy dense foods.  Science demonstrates that the overarching controls of obesity are genetic (70%) rather than environmental (30%). Adoption studies relating to monozygotic twins demonstrate this. In view of the metabolic consequences of obesity, understanding why we get fat is extremely important to medical practitioners.

We are privileged to have a conversation in this podcast with Joseph Proietto, Professor Emeritus at the University of Melbourne in the Department of Medicine at Austin Health and an Endocrinologist who specialises in diabetes and obesity. Professor Proietto established the first Obesity Clinic in Victoria at the Royal Melbourne Hospital and is the head of Weight Control Clinic at Austin Health. He was the inaugural Sir Edward Dunlop medical research foundation Professor of Medicine and head of the Metabolic Disorders Research Group in the Department of Medicine, Austin Health, Joseph is on the executive of World Obesity and Chair of the Clinical Care Committee.

In this conversation he discusses:

· Why we become fat

· The role of genetic and epigenetic factors

· Some of the important hormones controlling satiety and hunger

Please enjoy this very interesting and informative conversation with Professor Joe Proietto.

Useful references include:

www.endocrine.net.au

www.darebinweightlosssurgery.com.au

- vermontsouthmedicalcentre.com.au

- Body Weight Regulation – Essential Knowledge to Lose Weight and Keep It Off by Joseph Proietto. ISBN 9781514497005. Published 12 August 2016, Publisher Xlibris.

www.aihw.gov.au

- pubmed.ncbi.nlm.nih.gov

www.sciencedirect.com

To be a guest on the show or provide some feedback, I’d love to hear from you: manager@gihealth.com.au

Dr Luke Crantock MBBS, FRACP, is a gastroenterologist in practice for over 25 years. He is the founder of The Centre for GI Health, based in Melbourne Australia and is passionate about educating General Practitioners and patients on disease prevention and how to manage and improve their digestive health.

Read More